Publications

In Preparation

Elsilä, L.V., Nagaeva, E., Luukkonen, J-P., Korpi, E.R. On rewarding properties of serotonin agonists.

Elsilä, L.V. Ilkka, L., van den Broecke, L., Salovaara M., Korpi, E.R. Effects of LSD on extinction learning.

Elsilä, L.V., Nagaeva, E., Korpi, E.R. Effects of LSD on alcohol-seeking behaviour in group-housed mice.

Preprints



Published peer reviewed articles

* denotes 'Corresponding author'

Original research

Nagaeva, E., Schäfer, A., Linden, AM., Elsilä, L.V., Egorova, K., Umemori, J., Ryazantseva, M., Korpi, E.R. (2023)
Somatostatin-expressing neurons in the ventral tegmental area innervate specific forebrain regions and are involved in stress related responses.
eNeuro 10(8): ENEURO.0149-23.2023. DOI:10.1523/ENEURO.0149-23.2023


Moliner, R., Girych, M., Brunello C.A., Kovaleva, V., Biojone, C., Enkavi, G., Antenucci, L., Kot, E.F., Goncharuk, S.A., Kaurinkoski, K., Kuutti, M., Fred, S.M., Elsilä, L.V., Sakson, S., Cannarozzo, C., Diniz, C.R.A.F., Seiffert, N., Rubiolo, A. Haapaniemi, H., Meshi, E., Nagaeva, E. Öhman, T., Rog, T., Kankuri, E., Vilar, M., Varjosalo, M., Korpi, E.R., Permi, P., Mineev ,K.S., Saarma, M., Vattulainen, I., Casarotto, P.C., Castrén, E. (2023) 

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB. 

Nature Neuroscience 26: 1032–1041 DOI: 10.1038/s41593-023-01316-5


Elsilä, L.V.*, Harkki, J., Enberg, E., Martti, A., Linden, AM., Korpi, E.R. (2022) 

Effects of acute lysergic acid diethylamide on intermittent ethanol and sucrose drinking and intracranial self-stimulation in C57BL/6 mice

Journal of Psychopharmacology 36(7): 860–874 DOI: 10.1177/02698811221104641 


Grotell, M., Abdurakhmanova, S., Elsilä, L.V., Korpi, E.R. (2021) 

Mice Lacking GABAA Receptor δ Subunit Have Altered Pharmaco-EEG Responses to Multiple Drugs. 

Frontiers in Pharmacology 12:706894. DOI: 10.3389/fphar.2021.706894


Elsilä, L.V.*, Korhonen, N., Hyytiä, P., Korpi, E. R., (2020) 

Acute LSD does not influence reward-driven decision-making of C57BL/6 mice in the Iowa Gambling Task. 

Frontiers in Pharmacology 11:602770. DOI: 10.3389/fphar.2020.602770


Nagaeva, E., Zubarev, I., Bengtsson Gonzales, C., Forss, M., Nikouei, K., de Miguel, E., Elsilä, L., Linden, A. M., Hjerling-Leffler, J., Augustine, G. J., & Korpi, E. R. (2020). 

Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area.

eLife 9, e59328. DOI: 10.7554/eLife.59328


de Miguel, E., Vekovisceheva, O., Elsilä, L.V., Panhelainen, A., Kankuri, E., Aitta-aho, T., & Korpi, E.R. (2019). 

Conditioned aversion and neuroplasticity induced by a superagonist of extrasynaptic GABAA receptors: correlation with activation of the oval BNST neurons and CRF mechanisms.

Frontiers in Molecular Neuroscience 12, 130. DOI: 10.3389/fnmol.2019.00130

Reviews

Hynninen, E., Moliner, R., Ekelund, J., Korpi, E., Elsilä, L.* (2020)
Psykedeelien kliiniset mahdollisuudet ja biologiset mekanismit. (“Clinical opportunities and biological mechanisms of psychedelics drugs”; in Finnish)
Duodecim 136(13):1531-9 

Published peer reviewed meeting abstracts


Elsilä, L., Harkki, J., Enberg, E., Martti, A., Linden, A-M., Korpi, E.R. (2021). P.0294 Lysergic acid diethylamide acutely reduces intermittent ethanol intake without observable effects on sucrose consumption of intracranial stimulation reward in mice. 

European Neuropsychopharmacology, 53, S212 DOI: 10.1016/j.euroneuro.2021.10.278 PDF


Moliner, R., Elsilä, L., Casarotto, P., Korpi, E., & Castrén, E. (2020). P. 210 A single dose of LSD facilitates long-lasting fear erasure in mice. 

European Neuropsychopharmacology, 31, S26. DOI: 10.1016/j.euroneuro.2019.12.036


Elsilä, L., De Miguel, E., & Korpi, E. R. (2018). P. 2.036-Somatostatin-expressing neurons in the bed nucleus of stria terminalis in anxiety-and addiction-related behaviours in mice. 

European Neuropsychopharmacolgy, 28, S49-S47. DOI: 10.1016/j.euroneuro.2017.12.075

Publications intended for professional communities


Elsilä, L. (2020). Missä viipyvät biosimilaarit?
Proviisorilehti, (2), 22–23. Issuu reader

(“Where are the biosimilars lingering?”; in Finnish)

 

Elsilä, L. (2019). Radikaaleilla teknologioilla yksilöllistä hoitoa.
Proviisorilehti, (2), 24. Issuu reader

(“Personalised care with radical technologies”; in Finnish)

 

Elsilä, L. (2019). Turvallisessa lääkehoidossa on tilaa asiantuntijuudelle.
Proviisorilehti, (1), 17. Issuu reader

(“There is room for expertise in safe medication”; in Finnish)

 

Elsilä, L. (2018). Antibioottiresistenssi - jätevedessä sen alku ja loppu.
Proviisorilehti, (1), 22–23. Issuu reader

(“Antibiotic resistance – sewage as both the start and the end”; in Finnish)

 

Elsilä, L. (2017). Rekisteritutkimus ja biopankit: kahdesta huipusta yhdeksi kärjeksi.
Proviisorilehti, (2), 16-17. Issuu reader
(“Register research and biobanks: from two tops to one spearhead”; in Finnish)

Theses


Elsilä, L. (2018). Somatostatin-expressing neurons in the bed nucleus of stria terminalis
Master’s thesis; Faculty of Pharmacy, University of Helsinki
(permanent link)


Elsilä, L. (2014). Geeni- ja soluhoidot silmän takaosan sairauksien hoidossa
(Gene and cell therapies in the treatment of disorders of the posterior segment of the eye)
Bachelor’s thesis, literature review; Faculty of Pharmacy, University of Helsinki